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You can very easily reduce the appearance of wrinkles with the use of a moisturizer. Most of the cosmetic treatments are variations on moisturizers; they immediately reduce the appearance of fine lines by 15%–20%. Preventing their appearance is a different issue. The daily use of retinoids can prevent the appearance of wrinkles; they penetrate into the skin, can work on the extracellular matrix — the collagen and elastin fibers. Source: Dr. Ushma Neill